Both natural and social sciences have made significant contributions to our understanding of the challenges and issues affecting our societies and planet. Notwithstanding that, it is now clear that new approaches are urgently needed if science is to be effectively used to make rapid progress. Following the release of Unleashing Science, coordinated by the ISC, the Council established the Global Commission on Science Missions for Sustainability in 2021 to explore how these recommendations might be condensed to practice.

This report summarizes the conclusions reached after extensive consultation with experts, detailed in the accompanying TAG report “A model for implementing mission science for sustainability.” As part of the proposed shift in how we tackle the 2030 Agenda and its SDGs with greater expediency, the ISC Global Commission is calling for science in support of progress towards the SDGs to be undertaken and supported differently. We firmly believe that by better integrating science with other perspectives, we can achieve what the 2030 Agenda set out to do: creating the conditions for a fairer and more sustainable world, while living within planetary boundaries.